Facharzt für Rheumatologie und Allgemeine Innere Medizin
Leitender Arzt Rheumatologie
Profil
Kompetenzen
Publikationen
Forschung
News
Sprachen
Deutsch, Englisch, Italienisch, Französisch
Berufserfahrung
| 2014–2017 | Leiter Subzentrum für seltene rheumatologische Erkrankungen am Zentrum für seltene Erkrankungen der Universitätsklinik Bonn (ZSEB) |
| 2012–2017 | Leiter Fachbereich Internistische Rheumatologie (Oberarzt), Medizinische Klinik und Poliklinik III, Universitätsklinik Bonn |
| 2012–2016 | 1. Vorsitzender Kooperatives Rheumazentrum Aachen-Köln-Bonn |
| 2012–2016 | Facharztprüfer bei der Ärztekammer Nordrhein, Düsseldorf |
| 2008–2012 | Leiter Fachbereich Internistische Rheumatologie (Oberarzt), Medizinische Klinik und Poliklinik I, Universitätsklinik Bonn |
| 2001–2008 | Fachbereich Internistische Rheumatologie (seit 2003 Oberarzt) Medizinische Klinik und Poliklinik I, Universitätsklinik Bonn |
| 1999–2001 | Weiterbildung Internistische Rheumatologie, Seidel-Klinik Bad Bellingen (Baden-Württemberg) |
| 1996–1999 | Assistenzarzt Innere Medizin, Medizinische Universitäts-Poliklinik Universitätsklinik Bonn |
| 1993–1994 | Arzt im Praktikum Innere Medizin, St. Josef-Hospital, Bonn |
Ausbildung
| 2010 | Habilitation Innere Medizin an der Universität Bonn |
| 1995–1996 | Marie Curie Stipendium Humankapital und Mobilität der Europäischen Union Hôpital Henri Mondor, Créteil/Paris |
| 1993 | Promotion Institut für Anatomie der Universität-Gesamthochschule Essen |
| 1989–1992 | Medizinstudium Universität-Gesamthochschule Essen, Abschluss |
| 1986–1989 | Studium Neurowissenschaften University of Texas Medical Branch (UTMB) in Galveston, USA |
| 1986–1989 | Forschungsprojekt Neurowissenschaften University of Texas Medical Branch (UTMB) in Galveston, USA |
| 1985–1986 | Medizinstudium Universität-Gesamthochschule Essen |
| 1983–1985 | Medizinstudium Georg-August-Universität Göttingen, Deutschland |
| 1983 | Università di Padova, Facoltà di Medicina e Chirurgia, Italien |
Mitgliedschaften
- International Society for Neurochemistry
- Marie-Curie-Association
- Deutsche Gesellschaft für Rheumatologie
- Kooperatives Rheumazentrum Aachen-Köln-Bonn
- Deutsche Gesellschaft für Innere Medizin
- American College of Rheumatology
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- Erkrankungen der inneren Organe, des Bewegungsapparats und autoimmune Erkrankungen
- Prüfarzt für klinische Studien
- Bottenstein JE, Hunter SF, Seidel MF. (1988) CNS neuronal cell line-derived factors regulate gliogenesis in neonatal rat brain cultures. J. Neurosci. Res. 20: 291.
- Seidel MF, Simard JM, Hunter SF, Campbell GA. (1991) Isolation of arteriolar microvessels and culture of smooth muscle cells from guinea pig cerebral cortex. Cell Tissue Res. 265: 579.
- Seidel MF, Keck R, Vetter H. (1997) ICAM-1/ LFA-1 expression in acute osteodestructive joint lesions in rats with collagen-induced arthritis. J. Histochem. Cytochem. 45(9): 1247.
- Seidel MF, Junier MP, Vetter H. (2003) Molecular cloning and sequence analysis of variant TNF-alpha transcripts do not indicate a significant role of gene polymorphism in collagen-induced arthritis. Clin. Exp. Rheumatol. 21(3): 414.
- Seidel MF, Ulrich-Merzenich G, Vetter H, Stratz T, Müller W. (2004) Normal concentrations of serum hyaluronic acid in patients with primary fibromyalgia syndrome. Clin. Exp. Rheumatol. 22 (1): 137.
- Seidel MF, Koch FW, Vetter H. (2004) Macrophage-like synoviocytes display phenotypic polymorphisms in a serum-free tissue culture medium. Rheumatol. Int. 26: 244.
- Fiebich BL, Akundi RS, Seidel M, Geyer V, Haus U, Müller W, Stratz T, Candelario-Jalil E. (2004) Expression of 5-HT3A receptors in cells of the immune system. Scand. J. Rheumatol. (Suppl. 119): 9.
- Seidel MF, Ulrich-Merzenich G, Fiebich B, Candelario-Jalil E, Koch FW, Vetter H. (2004) Tropisetron inhibits serotonin-induced PGE2 release from macrophage-like synovial cells in serum-free tissue culture. Scand. J. Rheumatol. Suppl. 119: 33.
- Seidel MF, Weinreich GF, Stratz T, Müller W. (2007) 5-HT3 receptor antagonists regulate autonomic cardiac dysfunction in primary fibromyalgia syndrome. Rheumatol. Int. 27 (11): 1025.
- Seidel M, Tsalik J, Vetter H, Müller W. (2007) Substance P in Rheumatic Diseases. Curr. Rheumat. Rev. 3: 17.
- Seidel MF, Belda Domene A, Vetter H. (2007) Differential diagnoses of suspected Lyme borreliosis or post-Lyme-disease syndrome. Eur. J. Clin. Microbiol. Infect. Dis. 26(9): 611.
- Walker UA, Tyndall A, Czirják L, Denton C, Farge-Bancel D, Kowal-Bielecka O, Müller-Ladner U, Bocelli-Tyndall C, Matucci-Cerinic M and EUSTAR Co-authors. (2007) Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database. Ann. Rheum. Dis. 66; 754.
- Seidel MF, Fiebich BL, Ulrich-Merzenich G, Candelario-Jalil E, Koch FW, Vetter H. (2008) Serotonin mediates PGE(2) overexpression through 5-HT(2A) and 5-HT (3) receptor subtypes in serum-free tissue culture of macrophage-like synovial cells. Rheumatol. Int. 28: 1017.
- Seidel MF, Herguijuela M, Forkert R, Otten U. (2010) Nerve growth factor in rheumatic diseases. Semin. Arthritis Rheum. 40(2): 109.
- Allanore Y, Meune C, Vonk MC, Airo P, Hachulla E, Caramaschi P, Riemekasten G, Cozzi F, Beretta L, Derk CT, Komósi A, Farge D, Balbir A, Riccieri V, Distler O, Chialà A, Del Papa N, Simic Pasalic K, Ghio M, Stamenkovic B, Rednic S, Host N, Pellerito R, Zegers E, Kahan A, Walker UA, Matucci-Cerinic M. and EUSTAR Co-authors. (2009) Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of systemic sclerosis patients. Ann. Rheum. Dis. 69: 218.
- Avouac J, Walker U, Tyndall A, Kahan A, ..., Seidel M et al.. (2010) Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database. J. Rheumatol. 37(7): 1488.
- Hügle T, Schuetz P, Daikeler T, Tyndall A, Matucci-Cerinic M, Walker UA, van Laar JM, EUSTAR coauthors. (2011) Late Onset Systemic Sclerosis - A systematic survey of the EULAR Scleroderma Trials and Research (EUSTAR) group database. Rheumatology 50(1): 161.
- Seidel MF, Müller W. (2011) Differential pharmacotherapy for subgroups of fibromyalgia patients with specific consideration of 5-HT3 receptor antagonists. Exp. Opin. Pharm. 12(9): 1381.
- Distler JH, Jordan S, Airo P, Alegre-Sancho JJ, Allanore Y, Balbir Gurman A, Caporali R, Caramaschi P, Carreira PE, Chizzolini C, Cutolo M, Tuncay Duruöz M, Farge-Bancel D, Hesselstrand R, Iannone F, De Keyser F, Kucharz EJ, Launay D, García de la Peña Lefebvre P, Lukacova O, Marasini B, Martinovic D, Marques Neto JF, Radic M, Rednic S, Riemekasten G, Rovensky J, Seidel MF, Senel S, Smith V, Sunderkötter C, Ton E, van Laar JM, Matucci-Cerinic M, Müller Ladner U, Distler O. (2011) Is there a role for TNFα antagonists in the treatment of SSc? EUSTAR expert consensus development using the Delphi technique. Clin. Exp. Rheumatol. 29(2 Suppl 65): S40.
- Seidel MF. (2012) Local injections of serotonin type-3 receptor antagonists as a therapeutic option in rheumatology. Fut. Med. Chem. 4(6): 705.
- Seidel MF, Lane NE. (2012) Control of arthritis pain with anti-nerve-growth factor: risk and benefit. Curr. Rheumatol. Rep. 14(6): 583.
- Ulrich-Merzenich G, Kelber O, Koptina A, Freischmidt A, Heilmann J, Müller J, Zeitler H, Seidel MF, Ludwig M, Heinrich EU, Winterhoff H. (2012) Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine. Phytomedicine 19(10): 930.
- Seidel MF, Wise BL, Lane NE. (2013 ) Nerve growth factor: an update on the science and therapy. Osteoarthritis Cartilage. 21(9): 1223.
- Elhai M, Avouac J, Walker UA, Matucci-Cerinic M, Riemekasten G, Airò P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Balbir Gurman A, Braun-Moscovici Y, Damjanov N, Ananieva LP, Scorza R, Jimenez S, Busquets J, Li M, Müller-Ladner U, Kahan A, Distler O, Allanore Y; EUSTAR co-authors. (2014) A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study. Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2014-206386.
- Maurer B, Graf N, Michel BA, Müller-Ladner U, Czirják L, Denton CP, Tyndall A, Metzig C, Lanius V, Khanna D, Distler O; EUSTAR co-authors. (2014) Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database. Ann. Rheum. Dis. annrheumdis-2014-205226.
- Avouac J, Walker UA, Hachulla E, Riemekasten G, Cuomo G, Carreira PE, Caramaschi P, Ananieva LP, Matucci-Cerinic M, Czirjak L, Denton C, Ladner UM, Allanore Y; the EUSTAR collaborators*. (2014) Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study. Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2014-205295.
- Hachulla E, Clerson P, Airò P, Cuomo G, Allanore Y, Caramaschi P, Rosato E, Carreira PE, Riccieri V, Sarraco M, Denton CP, Riemekasten G, Pozzi MR, Zeni S, Mihai CM, Ullman S, Distler O, Rednic S, Smith V, Walker UA, Matucci-Cerinic M, Müller-Ladner U, Launay D; EUSTAR co-workers. (2015) Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR population. Rheumatology 54(7): 1262.
- Wirz EG, Jaeger VK, Allanore Y, Riemekasten G, Hachulla E, Distler O, Airò P, Carreira PE, Tikly M, Vettori S, Balbir Gurman A, Damjanov N, Müller-Ladner U, Distler J, Li M, Häusermann P, Walker UA, EUSTAR coauthors. (2015) Incidence and predictors of cutaneous manifestations during the early course of systemic sclerosis: a 10-year longitudinal study from the EUSTAR database. Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2015-207271.
- Ingegnoli F, Boracchi P, Gualtierotti R, Smith V, Cutolo M, Foeldvari I, EUSTAR co-authors. (2015) A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory study. Microvasc. Res. 102: 19.
- Dobrota R, Maurer B, Graf N, Jordan S, Mihai C, Kowal-Bielecka O, Allanore Y, Distler O; EUSTAR coauthors. (2016) Prediction of improvement in skin fibrosis in diffuse cutaneous systemic sclerosis: a EUSTAR analysis. Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2015-208024.
- Seidel MF, Fiebich B, Lieb K, Ulrich-Merzenich G, Koch FW (2017) Substance P-induced nerve growth factor overexpression is down-regulated by serotonin in serum-free cultured osteoarthritis macrophage-like synovial cells. Synergy 5 (Part A): 9. https://doi.org/10.1016/j.synres.2017.07.001
- Elhai M, Meune C, Boubaya M, Avouac J, ..., Seidel M, …, Allanore Y, and EUSTAR co-authors. (2017) Mapping and predicting systemic sclerosis-mortality in the last decade through a multicenter cohort study and a death certificates analysis. Rheum. Dis. 76(11):1897-1905. doi: 10.1136/annrheumdis-2017-211448
Deutschsprachige Beiträge
- Storch MJ, Seidel MF, Müller W. (1999) Methothrexat-Therapie beim SAPHO-Syndrom - eine Kasuistik. Akt. Rheumatol. 24: 180.
- Koch FW, Peters K, Seidel M. (2003) Injizierbare bioinerte Cellulosemischester-membranen als bmp-Carrier. Potentieller Einsatz zur fibroossären Stabilisierung der degenerativen Segmentlockerung nach dynamischer Neutralisation. Osteologie 1(Suppl. 1): 115.
- Koch FW, Seidel M, Peters K. (2003) Die klinische Wertigkeit von Ossifikation und reaktiver florider Periositis nach Kniegelenkendoprothetik. Eine retrospektive Studie an 331 Fällen. Orthopädische Praxis 1: 30.
- Peters KM und Dietmar König P. (2006) Fortbildung Osteologie: Heterotope Ossifikationen experimentelle und klinische Aspekte von Koch FW, Bastian P, Seidel M. ISBN 3-7985-1601-4 Taschenbuch. Steinkopff Darmstadt. 81-91.
- Riemekasten G, Hoffmann U, Sunderkötter C, Weiss N, Kuhn A, für das angiologisch-dermatologisch-rheumatologische DU-Expertenboard. (2012) Digitale Ulzera bei systemischer Sklerose: Diagnostik und Therapie. Dtsch. Med. Wochenschr. 137(01/02): 34.
- Seidel MF. (2013) Lebensqualität bei Arthrose erhalten. Was kann der Hausarzt tun? Der Hausarzt 11/13: 43.
- Neurogene Entzündung, Nerve Growth Factor und Serotonin
- Progressive Systemsklerose und systemischer Lupus erythematodes, Stimulation von peripheren Lymphozyten mit Nerve Growth Factor
- Soluble Adhäsionsmoleküle, Biomarker bei rheumatischen Erkrankungen
- 3-Tesla Magnetresonanztomographie, Rheumatoide Arthritis
